The Sala di Costantino was frescoed for Pope Clement VII (r. 1523-34) by Giulio Romano (1499-1546), a pupil of Raphael (1483-1520), with the aid of Francesco Penni and Raffaellino del Colle. The theme is the triumph of Christianity over paganism.
The Sala di Costantino, which was designed to be used for receptions and official ceremonies, takes its name from the emperor Constantine (r. 306-337), who officially recognised the Christian faith in 313, granting believers freedom of worship. On the walls are painted four episodes from Constantine's life, which testify to the defeat of paganism and the triumph of the Christian religion.
The Sala di Costantino is one of the four so-called Raphael Rooms (Stanze di Raffaello).